It is with great sadness and with the warmest thoughts we remember our friend and fellow researcher Professor Paolo Pelosi. Paolo was an essential member of the TTM-trial group from its start more than 15 years ago and we hope to carry on in his enthusiastic, positive and always collaborative spirit. He continued to improve, comment and celebrate good research up until only a few days ago. Our thoughts are with his family and also with his colleagues at San Martino in Genoa. For Paolos next passage we hope to hear a confirmation of a safe receipt! Vale!